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Vaccine Safety: Vaccines Are One of Public Health’s Great Accomplishments

Article

Richard G. Judelsohn

Volume 31.6, November / December 2007

Over the past decade, the public has been presented with a large amount of information about the safety of vaccines. Among the reasons for this interest is the widespread success of routine, universal immunization of infants and children, beginning in the 1940s. Previously common, dangerous, handicapping, potentially fatal diseases (vaccine-preventable diseases) have been wiped out with this policy (see table on next page). As the last century drew to a close, immunization was declared the greatest public health achievement in the United States in the twentieth century.

The list of licensed and recommended vaccines has been growing, and not just for infants and children. There are now schedules from professional societies, such as the

American Academy of Family Physicians (AAFP) and the American College of Obstetricians and Gynecologists (ACOG), and public agencies (e.g., the U.S. Centers for Disease Control and Prevention–CDC and most state health departments) that indicate what vaccines should be given and when for adolescents, adults, and specific vulnerable populations.

The considerable focus on vaccines and their safety in our information-overloaded society is not surprising, with a surplus of articles in magazines, books, parenting guides, and on the Internet, and stories on radio and television. While these occasionally highlight the benefits of immunization, “No One Got Sick or Died from a Vaccine-Preventable Disease Today” is not a very exciting story, so more often the emphasis in the media is on speculation that a vaccine caused a health problem. Furthermore, the widespread availability of litigation and liberal tort in the U.S. has encouraged lawsuits claiming harm from vaccines. Finally, it’s human nature to assume cause and effect when something bad happens, so a vaccination is an attractive target when administered before the onset of a medical condition.

Unfortunately, most of the public receives a lot of health information from lay sources rather than their physicians. Professional knowledge of immunization is grounded in science—microbiology, immunology, epidemiology, and statistics. Vaccines are licensed by the U.S. Federal Drug Administration (FDA) only when proven safe and effective. Recommendations for use are promulgated by committees of scientific experts composed of academics, clinicians, and other caregivers who are passionately devoted to our citizens’ health and safety. The committees’ conclusions, and the rationale for them, are shared with practicing physicians, who are the most reliable source of information for patients. This process is the foundation that has led to the conclusion that licensed vaccines are safe, and the fears that vaccines are harmful are unfounded.

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Nevertheless, to address these unfounded fears, these and other groups of scientific experts have undertaken investigations to determine possible relationships between vaccines and autism, asthma, diabetes, multiple sclerosis, SIDS, and other diseases. No studies have yet established a causal link between vaccines and these diseases. For example:

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Many of us recall that only two generations ago we had schoolmates who limped or had withered arms due to the paralytic polio they were infected with. That disease is now extinct in the U.S. because of the universal use of polio vaccine. During my training, I cared for children made deaf from measles, infants blind and retarded from rubella, and those who died from bacteria like pneumococcus and meningococcus. With vaccination, those conditions no longer occur. As a physician in my early years of practice, the threat of infection with bacteria called Haemophilus influenza type B (Hib) loomed large for my patients and their families, the outcomes of brain damage or death being distinct possibilities. A vaccine was invented, adopted as policy, and given to U.S. infants and children. I’m pleased to say I no longer worry about Hib infection.

Despite scientific proof and a long track record of vaccine safety, we see public policy based on junk beliefs, misinformation, fear, and mass hysteria. In 2006, a number of legislative bodies passed, and executives signed, bills prohibiting use of vaccines containing thimerosal. From a practical perspective, these restrictions mean little, since all but a few influenza vaccines do not contain thimerosal. But such policies send a bad message: that the vaccines that have virtually eradicated many diseases, constituting one of the greatest public health accomplishments of the past century, are dangerous. Furthermore, these policies denigrate our informed medical and scientific communities. This is a disservice to our citizens and endangers us all.

Richard G. Judelsohn

Richard G. Judelsohn, MD, is Clinical Associate Professor, School of Medicine, University at Buffalo, and Medical Director, Erie County Department of Health.